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| Catalog No ： | IPB14350 |
| Reactivity： | Human; Mouse; |
| Applications： | WB |
| Dilution： | WB: 1:500-2000 |
| Gene Name： | ZNF259 ZPR1 |
| Protein Name： | ZPR1 |
| Human Gene Id： | 8882 |
| Swiss-Prot： | O75312 |
| Formulation： | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | Nucleus Nucleus, nucleolus Nucleus, gem Nucleus, Cajal body Cytoplasm, perinuclear region Cytoplasm Cell projection, axon Cell projection, growth cone Colocalized with SMN1 in Gemini of coiled bodies (gems), Cajal bodies, axon and growth cones of neurons (By similarity) Localized predominantly in the cytoplasm in serum-starved cells growth arrested in G0 of the mitotic cell cycle Localized both in the nucleus and cytoplasm at the G1 phase of the mitotic cell cycle Accumulates in the subnuclear bodies during progression into the S phase of the mitotic cell cycle Diffusely localized throughout the cell during mitosis Colocalized with NPAT and SMN1 in nuclear bodies including gems (Gemini of coiled bodies) and Cajal bodies in a cell cycle-dependent manner Translocates together with EEF1A1 from the cytoplasm to the nucleolus after treatment with mitogens Colocalized with EGFR in the cytoplasm of quiescent cells Translocates from the cytoplasm to the nucleus in a epidermal growth factor (EGF)-dependent manner |
| MW： | 50490 |
| Background： | The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells The encoded protein interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal differentiation and axonal growth Defects in this gene or the SMN1 gene can cause spinal muscular atrophy Two transcript variants encoding different isoforms have been found for this gene |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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