中文
EnglishCatalog No : | IPB14030 |
Reactivity: | Human; Mouse; |
Applications: | WB |
Dilution: | WB: 1:500-2000 |
Gene Name: | VPS16 |
Protein Name: | VPS16 |
Human Gene Id: | 64601 |
Swiss-Prot: | Q9H269 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Late endosome membrane; Peripheral membrane protein; Cytoplasmic side Lysosome membrane; Peripheral membrane protein; Cytoplasmic side Early endosome Cytoplasmic vesicle, clathrin-coated vesicle Cytoplasmic vesicle, autophagosome Colocalizes with AP-3, clathrin, Rab5 and Rab7b (By similarity) Cytoplasmic, peripheral membrane protein associated with early endosomes and late endosomes:lysosomes |
MW: | 92290 |
Background: | Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles This gene encodes the human homolog of yeast class C Vps16 protein The mammalian class C Vps proteins are predominantly associated with late endosomes:lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome:lysosome pathway Two transcript variants encoding different isoforms have been found for this gene |
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