中文
EnglishCatalog No : | IPB12176 |
Reactivity: | Human; Mouse; |
Applications: | WB |
Dilution: | WB: 1:500-2000 |
Gene Name: | ATP8A1 ATPIA |
Protein Name: | AT8A1 |
Human Gene Id: | 10396 |
Swiss-Prot: | Q9Y2Q0 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Multi-pass membrane protein Cytoplasmic granule Cell membrane Endoplasmic reticulum Golgi apparatus Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not TMEM30B In the presence of TMEM30A, predominantly located in cytoplasmic punctate structures and localizes to the plasma membrane Localizes to plasma membranes of red blood cells (By similarity) |
MW: | 128040 |
Background: | The P-type adenosinetriphosphatases (P-type ATPases) are a family of proteins which use the free energy of ATP hydrolysis to drive uphill transport of ions across membranes Several subfamilies of P-type ATPases have been identified One subfamily catalyzes transport of heavy metal ions Another subfamily transports non-heavy metal ions (NMHI) The protein encoded by this gene is a member of the third subfamily of P-type ATPases and acts to transport amphipaths, such as phosphatidylserine Two transcript variants encoding different isoforms have been found for this gene |
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