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EnglishCatalog No : | IPB4227 |
Reactivity: | Human; Mouse; Rat |
Applications: | IHC; IF/ICC; ELISA |
Dilution: | IHC: 1:50-1:200 IF: 1:50-1:200 ELISA: 1:5000 |
Gene Name: | LRRK1 |
Protein Name: | Leucine-rich repeat serine/threonine-protein kinase 1 |
Human Gene Id: | 79705 |
Swiss-Prot: | Q38SD2 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Cytoplasm |
MW: | 227843 |
Background: | This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion:homing receptors The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy Alternatively spliced transcript variants have been found for this gene |
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