中文
EnglishCatalog No : | IPB4225 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB; ELISA |
Dilution: | WB: 1:500-1:2000 ELISA: 1:40000 |
Gene Name: | LRP3 |
Protein Name: | Low-density lipoprotein receptor-related protein 3 |
Human Gene Id: | 4037 |
Swiss-Prot: | O75074 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Membrane; Single-pass type I membrane protein Membrane, coated pit |
MW: | 82884 |
Background: | caution: It is uncertain whether Met-1 or Met-23 is the initiator,domain: The elongin BC complex binding domain is also known as BC-box with the consensus [APST]-L-x(3)-C-x(3)-[AILV],function: Probable substrate recognition component of an ECS (Elongin BC-CUL2:5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins,pathway: Protein modification; protein ubiquitinationPTM: Phosphorylated upon DNA damage, probably by ATM or ATR,sequence caution: Translation N-terminally extended,similarity: Contains 7 LRR (leucine-rich) repeats,subunit: Part of an E3 ubiquitin-protein ligase complex with Elongin BC (TCEB1 and TCEB2), RBX1 and CUL5 Component of a probable ECS(LRRC41) complex which contains CUL5, RNF7:RBX2, Elongin BC and LRRC41 Interacts with CUL5, RNF7, TCEB1 and TCEB2 |
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