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LRP3 Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB4225

库存:现货
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Catalog No :IPB4225
Reactivity:Human; Mouse; Rat
Applications:WB; ELISA
Dilution:WB: 1:500-1:2000 ELISA: 1:40000
Gene Name:LRP3
Protein Name:Low-density lipoprotein receptor-related protein 3
Human Gene Id:4037
Swiss-Prot:O75074
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Membrane; Single-pass type I membrane protein Membrane, coated pit
MW:82884
Background:caution: It is uncertain whether Met-1 or Met-23 is the initiator,domain: The elongin BC complex binding domain is also known as BC-box with the consensus [APST]-L-x(3)-C-x(3)-[AILV],function: Probable substrate recognition component of an ECS (Elongin BC-CUL2:5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins,pathway: Protein modification; protein ubiquitinationPTM: Phosphorylated upon DNA damage, probably by ATM or ATR,sequence caution: Translation N-terminally extended,similarity: Contains 7 LRR (leucine-rich) repeats,subunit: Part of an E3 ubiquitin-protein ligase complex with Elongin BC (TCEB1 and TCEB2), RBX1 and CUL5 Component of a probable ECS(LRRC41) complex which contains CUL5, RNF7:RBX2, Elongin BC and LRRC41 Interacts with CUL5, RNF7, TCEB1 and TCEB2

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