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Lfc Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB4186

库存:现货
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产品信息

Catalog No :IPB4186
Reactivity:Human; Mouse; Rat
Applications:WB; IHC; ELISA
Dilution:WB: 1:500-1:2000 IHC: 1:50-1:200 ELISA: 1:20000
Gene Name:ARHGEF2
Protein Name:Rho guanine nucleotide exchange factor 2
Human Gene Id:9181
Swiss-Prot:Q92974
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Cytoplasm, cytoskeleton Cytoplasm Cell junction, tight junction Golgi apparatus Cytoplasm, cytoskeleton, spindle Cell projection, ruffle membrane Cytoplasmic vesicle Localizes to the tips of cortical microtubules of the mitotic spindle during cell division, and is further released upon microtubule depolymerization (PubMed:15827085) Recruited into membrane ruffles induced by Sflexneri at tight junctions of polarized epithelial cells (PubMed:19043560) Colocalized with NOD2 and RIPK2 in vesicles and with the cytoskeleton (PubMed:21887730)
MW:111543
Background:This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding Alternative splicing of this gene results in multiple transcript variants

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