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EnglishCatalog No : | IPB3900 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB; IHC; ELISA |
Dilution: | WB: 1:500-1:2000 IHC: 1:50-1:200 ELISA: 1:40000 |
Gene Name: | IL32 |
Protein Name: | Interleukin-32 |
Human Gene Id: | 9235 |
Swiss-Prot: | P24001 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Secreted |
MW: | 26676 |
Background: | The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2:GM-CSF), and interleukin 5 (IL5) The binding of this protein to IL3 depends on the beta subunit The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3 This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y Alternatively spliced transcript variants encoding distinct isoforms have been found |
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