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| Catalog No ： | IPB3849 |
| Reactivity： | Human; Mouse; Rat |
| Applications： | WB; IHC; ELISA |
| Dilution： | WB: 1:500-1:2000 IHC: 1:50-1:200 ELISA: 1:20000 |
| Gene Name： | IL12A |
| Protein Name： | Interleukin-12 subunit alpha |
| Human Gene Id： | 3592 |
| Swiss-Prot： | P29459 |
| Formulation： | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | Secreted |
| MW： | 24874 |
| Background： | This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development This cytokine has been found to be important for sustaining a sufficient number of memory:effector Th1 cells to mediate long-term protection to an intracellular pathogen Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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