中文
EnglishCatalog No : | IPB3683 |
Reactivity: | Human; Mouse; |
Applications: | IHC; WB; ELISA |
Dilution: | WB: 1:500-2000 IHC: 1:50-1:200 ELISA: 1:20000 |
Gene Name: | NSG2 |
Protein Name: | Neuron-specific protein family member 2 |
Human Gene Id: | 51617 |
Swiss-Prot: | Q9Y328 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Membrane; Single-pass type II membrane protein Golgi apparatus, trans-Golgi network membrane Cell projection, dendrite Endosome membrane Early endosome membrane Late endosome membrane Lysosome lumen Cytoplasmic vesicle membrane Golgi apparatus, Golgi stack membrane Endosome, multivesicular body membrane Endocytosed from the cell surface, thus entered into early endosomes, trafficks to late endosomes and degradates in lysosomes (By similarity) Mainly Golgi stack, but also found in small vacuolar organelles and multivesicular bodies Found in both stationary and motile endosomes (By similarity) |
MW: | 19085 |
Background: | This gene encodes a member of the homeodomain-containing superfamily of transcription factors The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer Multiple transcript variants encoding different isoforms have been found for this gene |
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