中文
English
| Catalog No ： | IPB0344 |
| Reactivity： | Human; Mouse; |
| Applications： | WB; IHC-p; ELISA |
| Dilution： | WB: 1:500-1:2000 IHC: 1:50-1:200 ELISA: 1:10000 |
| Gene Name： | BID |
| Protein Name： | BH3-interacting domain death agonist |
| Human Gene Id： | 637 |
| Swiss-Prot： | P55957 |
| Formulation： | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | Cytoplasm Mitochondrion membrane Mitochondrion outer membrane When uncleaved, it is predominantly cytoplasmic [BH3-interacting domain death agonist p15]: Mitochondrion membrane Translocates to mitochondria as an integral membrane protein [BH3-interacting domain death agonist p13]: Mitochondrion membrane Associated with the mitochondrial membrane [Isoform 1]: Cytoplasm [Isoform 3]: Cytoplasm [Isoform 2]: Mitochondrion membrane A significant proportion of isoform 2 localizes to mitochondria, it may be cleaved constitutively |
| MW： | 21995 |
| Background： | This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2 The encoded protein is a member of the BCL-2 family of cell death regulators It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
join our baijia list to stay up to date and get notices about our new releases!
