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| Catalog No ： | IPB0323 |
| Reactivity： | Human; Mouse; Rat |
| Applications： | WB; IHC-p; ELISA |
| Dilution： | WB: 1:500-1:2000 IHC-p: 1:100-1:200 ELISA: 1:20000 |
| Gene Name： | BIN1 |
| Protein Name： | Myc box-dependent-interacting protein 1 |
| Human Gene Id： | 274 |
| Swiss-Prot： | O00499 |
| Formulation： | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | [Isoform BIN1]: Nucleus Cytoplasm Endosome Cell membrane, sarcolemma, T-tubule [Isoform IIA]: Cytoplasm |
| MW： | 64699 |
| Background： | This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process Studies in mouse suggest that this gene plays an important role in cardiac muscle development Alternate splicing of the gene results in several transcript variants encoding different isoforms Aberrant splice variants expressed in tumor cell lines have also been described |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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