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EnglishCatalog No : | IPB0305 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB; IHC-p; IF/ICC; ELISA |
Dilution: | WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:50-1:200 ELISA: 1:20000 |
Gene Name: | RPS6KB1 |
Protein Name: | Ribosomal protein S6 kinase beta-1 |
Human Gene Id: | 6198 |
Swiss-Prot: | P23443 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Cell junction, synapse, synaptosome Mitochondrion outer membrane Mitochondrion Colocalizes with URI1 at mitochondrion [Isoform Alpha I]: Nucleus Cytoplasm [Isoform Alpha II]: Cytoplasm |
MW: | 59140 |
Background: | This gene encodes a member of the ribosomal S6 kinase family of serine:threonine kinases The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation Activity of this gene has been associated with human cancer Alternatively spliced transcript variants have been observed The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations There are two pseudogenes for this gene on chromosome 17 |
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