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Bcl-w Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB0201

库存:现货
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Catalog No :IPB0201
Reactivity:Human; Mouse; Rat
Applications:WB; IHC-p; IF/ICC; ELISA
Dilution:WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:50-1:200 ELISA: 1:10000
Gene Name:BCL2L2
Protein Name:Bcl-2-like protein 2
Human Gene Id:599
Swiss-Prot:Q92843
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Mitochondrion membrane; Peripheral membrane protein Loosely associated with the mitochondrial membrane in healthy cells During apoptosis, tightly bound to the membrane
MW:20774
Background:This gene encodes a member of the BCL-2 protein family The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis Alternative splicing results in multiple transcript variants Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene

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