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MMP-3 Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB0186

库存:现货
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Catalog No :IPB0186
Reactivity:Human; Mouse; Rat
Applications:WB; IHC-p; IF/ICC; ELISA
Dilution:WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:50-1:200 ELISA: 1:10000
Gene Name:MMP3
Protein Name:Stromelysin-1
Human Gene Id:4314
Swiss-Prot:P08254
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Secreted, extracellular space, extracellular matrix
MW:53977
Background:Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation The gene is part of a cluster of MMP genes which localize to chromosome 11q223

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