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LXRα Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB0155

库存:现货
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Catalog No :IPB0155
Reactivity:Human; Mouse; Rat
Applications:WB; IHC-p; ELISA
Dilution:WB: 1:500-1:2000 IHC-p: 1:100-1:200 ELISA: 1:20000
Gene Name:NR1H3
Protein Name:Oxysterols receptor LXR-alpha
Human Gene Id:10062
Swiss-Prot:Q13133
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Nucleus Cytoplasm
MW:50396
Background:The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation This protein is highly expressed in visceral organs, including liver, kidney and intestine It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis Alternatively spliced transcript variants encoding different isoforms have been found for this gene

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