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IκB-α Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB0154

库存:现货
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Catalog No :IPB0154
Reactivity:Human; Mouse; Rat
Applications:WB; IHC-p; IF/ICC; ELISA
Dilution:WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:50-1:200 ELISA: 1:10000
Gene Name:NFKBIA
Protein Name:NF-kappa-B inhibitor alpha
Human Gene Id:4792
Swiss-Prot:P25963
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Cytoplasm Nucleus Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export
MW:35609
Background:This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains The encoded protein interacts with REL dimers to inhibit NF-kappa-B:REL complexes which are involved in inflammatory responses The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease

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