中文
EnglishCatalog No : | IPB0148 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB; ELISA |
Dilution: | WB: 1:500-2000 ELISA: 1:5000-20000 |
Gene Name: | MLF1IP CENPU ICEN24 KLIP1 PBIP1 |
Protein Name: | Centromere protein U (CENP-U) (Interphase centromere complex protein 24) (KSHV latent nuclear antigen-interacting protein 1) (MLF1-interacting protein) (Polo-box-interacting protein 1) (centromere protein of 50 kDa) (CENP-50) |
Human Gene Id: | 79682 |
Swiss-Prot: | Q71F23 |
Formulation: | Liquid in PBS containing 50% glycerol, and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Cytoplasm Nucleus Chromosome, centromere, kinetochore Localizes in the kinetochore domain of centromeres Colocalizes with PLK1 at the interzone between the inner and the outer kinetochore plates |
MW: | - |
Background: | The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128) MLF1IP, or CENPU, is an additional factor required for centromere assembly (Foltz et al, 2006 [PubMed 16622419]) |
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