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| Catalog No ： | IPB0146 |
| Reactivity： | Human; Mouse; Rat |
| Applications： | WB; IHC-p; ELISA |
| Dilution： | WB: 1:500-1:2000 IHC: 1:50-1:200 ELISA: 1:40000 |
| Gene Name： | CASP12 |
| Protein Name： | caspase12 |
| Human Gene Id： | 120329 |
| Swiss-Prot： | Q6UXS9 |
| Formulation： | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | endoplasmic reticulum,IPAF inflammasome complex,NLRP3 inflammasome complex,AIM2 inflammasome complex, |
| MW： | 38907/29429 |
| Background： | Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon The majority of human individuals have the premature stop codon and produce a truncated non-functional protein The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis Several alternatively spliced transcript variants have been noted for this gene |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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