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ABCA1 Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB0142

库存:现货
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Catalog No :IPB0142
Reactivity:Human; Mouse;
Applications:WB; ELISA
Dilution:WB: 1:500-2000 ELISA: 1:5000-20000
Gene Name:ABCA1 ABC1 CERP
Protein Name:ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1) (Cholesterol efflux regulatory protein)
Human Gene Id:19
Swiss-Prot:O95477
Formulation:Liquid in PBS containing 50% glycerol, and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Cell membrane; Multi-pass membrane protein Endosome
MW:-
Background:The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters ABC proteins transport various molecules across extra- and intracellular membranes ABC genes are divided into seven distinct subfamilies (ABC1, MDR:TAP, MRP, ALD, OABP, GCN20, White) This protein is a member of the ABC1 subfamily Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency

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