中文
EnglishCatalog No : | IPB0142 |
Reactivity: | Human; Mouse; |
Applications: | WB; ELISA |
Dilution: | WB: 1:500-2000 ELISA: 1:5000-20000 |
Gene Name: | ABCA1 ABC1 CERP |
Protein Name: | ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1) (Cholesterol efflux regulatory protein) |
Human Gene Id: | 19 |
Swiss-Prot: | O95477 |
Formulation: | Liquid in PBS containing 50% glycerol, and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Cell membrane; Multi-pass membrane protein Endosome |
MW: | - |
Background: | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters ABC proteins transport various molecules across extra- and intracellular membranes ABC genes are divided into seven distinct subfamilies (ABC1, MDR:TAP, MRP, ALD, OABP, GCN20, White) This protein is a member of the ABC1 subfamily Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency |
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