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CD63 Polyclonal Antibody

¥1900.00元/format:100ul

目录号:IPB0123

库存:现货
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Catalog No :IPB0123
Reactivity:Human; Mouse; Rat
Applications:IF/ICC; WB; IHC-p; ELISA
Dilution:IF: 1:50-200 WB: 1:500-1:2000 IHC-p: 1:100-1:200 ELISA: 1:20000
Gene Name:CD63
Protein Name:CD63 antigen
Human Gene Id:967
Swiss-Prot:P08962
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Cell membrane; Multi-pass membrane protein Lysosome membrane; Multi-pass membrane protein Late endosome membrane; Multi-pass membrane protein Endosome, multivesicular body Melanosome Secreted, extracellular exosome Cell surface Also found in Weibel-Palade bodies of endothelial cells (PubMed:10793155) Located in platelet dense granules (PubMed:7682577) Detected in a subset of pre-melanosomes Detected on intralumenal vesicles (ILVs) within multivesicular bodies (PubMed:21962903)
MW:25637
Background:The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility The encoded protein is a cell surface glycoprotein that is known to complex with integrins It may function as a blood platelet activation marker Deficiency of this protein is associated with Hermansky-Pudlak syndrome Also this gene has been associated with tumor progression Alternative splicing results in multiple transcript variants encoding different protein isoforms

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