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EnglishCatalog No : | IPB0122 |
Reactivity: | Human; Mouse; |
Applications: | WB; IHC-p; IF/ICC; ELISA |
Dilution: | WB: 1:500-1:2000 IHC-p: 1:100-1:200 ELISA: 1:20000 IF: 1:50-1:200 |
Gene Name: | PECAM1 |
Protein Name: | Platelet endothelial cell adhesion molecule |
Human Gene Id: | 5175 |
Swiss-Prot: | P16284 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Cell membrane; Single-pass type I membrane protein Cell surface expression on neutrophils is down-regulated upon fMLP or CXCL8:IL8-mediated stimulation [Isoform Long]: Cell membrane; Single-pass type I membrane protein Membrane raft Cell junction Localizes to the lateral border recycling compartment (LBRC) and recycles from the LBRC to the junction in resting endothelial cells [Isoform Delta15]: Cell junction Localizes to the lateral border recycling compartment (LBRC) and recycles from the LBRC to the junction in resting endothelial cells |
MW: | 82536 |
Background: | The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation |
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