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| Catalog No ： | IPB0106 |
| Reactivity： | Human; Mouse; |
| Applications： | WB; ELISA |
| Dilution： | WB: 1:500-2000 ELISA: 1:10000-20000 |
| Gene Name： | BECN1 GT197 |
| Protein Name： | Beclin-1 |
| Human Gene Id： | 8678 |
| Swiss-Prot： | Q14457 |
| Formulation： | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | Cytoplasm Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein Endosome membrane; Peripheral membrane protein Endoplasmic reticulum membrane; Peripheral membrane protein Mitochondrion membrane; Peripheral membrane protein Endosome Cytoplasmic vesicle, autophagosome Interaction with ATG14 promotes translocation to autophagosomes Expressed in dendrites and cell bodies of cerebellar Purkinje cells (By similarity) [Beclin-1-C 35 kDa]: Mitochondrion Nucleus Cytoplasm [Beclin-1-C 37 kDa]: Mitochondrion |
| MW： | 51896 |
| Background： | This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis Alternative splicing results in multiple transcript variants |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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