中文
EnglishCatalog No : | IPB0099 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB; IHC-p; IF/ICC; ELISA |
Dilution: | WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:50-1:200 ELISA: 1:20000 |
Gene Name: | VIM |
Protein Name: | Vimentin |
Human Gene Id: | 7431 |
Swiss-Prot: | P08670 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Cytoplasm Cytoplasm, cytoskeleton Nucleus matrix Cell membrane |
MW: | 53652 |
Background: | This gene encodes a member of the intermediate filament family Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling Mutations in this gene causes a dominant, pulverulent cataract |
SPECIES
APPLICATION
TITLE