中文
EnglishCatalog No : | IPB0097 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB; IHC-p; ELISA |
Dilution: | WB: 1:500-1:2000 IHC: 1:50-1:200 ELISA: 1:20000 |
Gene Name: | ACTA2 |
Protein Name: | Actin aortic smooth muscle |
Human Gene Id: | 59 |
Swiss-Prot: | P62736 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 005% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Cytoplasm, cytoskeleton |
MW: | 42009 |
Background: | The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility This actin is an alpha actin that is found in skeletal muscle Defects in this gene cause aortic aneurysm familial thoracic type 6 Multiple alternatively spliced variants, encoding the same protein, have been identified |
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