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Ki-67 Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB0064

库存:现货
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Catalog No :IPB0064
Reactivity:Human; Mouse; Rat
Applications:IHC-p; IF/ICC; ELISA
Dilution:IHC: 1:100-1:200  IF: 1:50-1:200   ELISA: 1:20000
Gene Name:MKI67
Protein Name:Antigen KI-67
Human Gene Id:4288
Swiss-Prot:P46013
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Chromosome Nucleus Nucleus, nucleolus Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the mitotic chromosome surface (PubMed:27362226) Associates with satellite DNA in G1 phase (PubMed:9510506) Binds tightly to chromatin in interphase, chromatin-binding decreases in mitosis when it associates with the surface of the condensed chromosomes (PubMed:15896774, PubMed:22002106) Predominantly localized in the G1 phase in the perinucleolar region, in the later phases it is also detected throughout the nuclear interior, being predominantly localized in the nuclear matrix (PubMed:22002106)
MW:360KD
Background:This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation Alternatively spliced transcript variants have been described A related pseudogene exists on chromosome X

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