中文
EnglishCatalog No : | IPB0062 |
Reactivity: | Human |
Applications: | WB;IHC;IF;ELISA |
Dilution: | WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. IF 1:100-300 |
Gene Name: | IL6 |
Protein Name: | Interleukin-6 |
Human Gene Id: | 3569 |
Swiss-Prot: | P05231 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Secreted |
MW: | 23KD |
Background: | This gene encodes a cytokine that functions in inflammation and the maturation of B cells In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis Alternative splicing results in multiple transcript variants |
SPECIES
APPLICATION
TITLE