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TGFβ3 Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB0044

库存:现货
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Catalog No :IPB0044
Reactivity:Human; Mouse; Rat; Monkey
Applications:WB; IHC-p; ELISA
Dilution:WB: 1:500-1:2000 IHC: 1:50-1:200 ELISA: 1:10000
Gene Name:TGFB3
Protein Name:Transforming growth factor beta-3
Human Gene Id:7043
Swiss-Prot:P10600
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:[Latency-associated peptide]: Secreted, extracellular space, extracellular matrix [Transforming growth factor beta-3]: Secreted
MW:47328
Background:This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer The mature peptide may also form heterodimers with other TGF-beta family members This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic

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