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EnglishCatalog No : | IPB0037 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB; IF/ICC; ELISA |
Dilution: | WB: 1:500-1:2000 ELISA: 1:20000 IF: 1:50-1:200 |
Gene Name: | TGFBR1 |
Protein Name: | TGF-beta receptor type-1 |
Human Gene Id: | 7046 |
Swiss-Prot: | P36897 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Cell membrane; Single-pass type I membrane protein Cell junction, tight junction Cell surface Membrane raft |
MW: | 55960 |
Background: | The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm The encoded protein is a serine:threonine protein kinase Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS) Multiple transcript variants encoding different isoforms have been found for this gene |
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