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CD3-ε Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB0021

库存:现货
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Catalog No :IPB0021
Reactivity:Human; Mouse; Rat
Applications:WB; IHC-p; ELISA
Dilution:WB: 1:500-1:2000 IHC: 1:50-1:200 ELISA: 1:5000
Gene Name:CD3E
Protein Name:T-cell surface glycoprotein CD3 epsilon chain
Human Gene Id:916
Swiss-Prot:P07766
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Cell membrane; Single-pass type I membrane protein
MW:23147
Background:The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha:beta and gamma:delta heterodimers, forms the T-cell receptor-CD3 complex This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11 The epsilon polypeptide plays an essential role in T-cell development Defects in this gene cause immunodeficiency This gene has also been linked to a susceptibility to type I diabetes in women

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