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CD1B Polyclonal Antibody

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¥1900.00元/format:100ul

目录号:IPB0007

库存:现货
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产品信息

Catalog No :IPB0007
Reactivity:Human; Mouse; Rat
Applications:IHC-p; ELISA
Dilution:IHC-p: 1:100-1:200 ELISA: 1:10000-20000
Gene Name:CD1B
Protein Name:T-cell surface glycoprotein CD1b (CD antigen CD1b)
Human Gene Id:910
Swiss-Prot:P29016
Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Cell membrane; Single-pass type I membrane protein Endosome membrane; Single-pass type I membrane protein Lysosome membrane; Single-pass type I membrane protein Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes
MW:-
Background:This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells The human genome contains five CD1 family genes organized in a cluster on chromosome 1 The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens

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