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GSK3β Monoclonal Antibody

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¥2080.00元/format:100ul

目录号:IMB0102

库存:现货
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Catalog No. :IMB0102
Reactivity:Human;Mouse;Rat;Monkey
Applications:WB; IHC-p; IF/ICC; FCM; ELISA
Gene Name:GSK3B
Protein Name:Glycogen synthase kinase-3 beta
Human Gene Id:2942
Swiss-Prot:P49841
Formulation:Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Source:Monoclonal, Mouse
Dilution:WB: 1:500-1:2000 IHC: 1:200-1:1000 IF: 1:200-1:1000 FCM: 1:200-1:400 ELISA: 1:10000
PurIF:ication:Affinity purIF:ication
Concentration:nan
Storage&Stability:-20°C/1 year
Background:The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modIF:ying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding dIF:ferent isoforms have been found for this gene.[provided by RefSeq, Sep 2009],
Subcellular Location.:Cytoplasm . Nucleus . Cell membrane . The phosphorylated form shows localization to cytoplasm and cell membrane (PubMed:20937854). The MEMO1-RHOA-DIAPH1 signaling pathway controls localization of the phosphorylated form to the cell membrane (PubMed:20937854). .
BiowMW:nan

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