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EnglishCatalog No. : | IMB0034 |
Reactivity: | Human;Mouse;Rat |
Applications: | WB; IHC-p; IF/ICC |
Gene Name: | FN1 |
Protein Name: | Fibronectin |
Human Gene Id: | 2335 |
Swiss-Prot: | P02751 |
Formulation: | PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol. |
Source: | Monoclonal, Mouse |
Dilution: | WB: 1:1000-2000 IF: 1:200 IHC: 1:50-300 |
PurIF:ication: | The antibody was affinity-purIF:ied from mouse ascites by affinity-chromatography using specIF:ic immunogen. |
Concentration: | nan |
Storage&Stability: | -20°C/1 year |
Background: | This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 dIF:ferent transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. The full-length nature of some variants has not been determined. [provided by RefSeq, Jan 2016], |
Subcellular Location.: | Secreted, extracellular space, extracellular matrix. |
BiowMW: | 262607 |
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