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CD1A Monoclonal Antibody

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¥2080.00元/format:100ul

目录号:IMB0004

库存:现货
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Catalog No. :IMB0004
Reactivity:Human
Applications:WB; IHC-p; IF/ICC; ELISA
Gene Name:CD1A
Protein Name:T-cell surface glycoprotein CD1a
Human Gene Id:909
Swiss-Prot:P06126
Formulation:Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Source:Monoclonal, Mouse
Dilution:WB: 1:500-1:2000 IHC: 1:200-1:1000 IF: 1:200-1:1000 ELISA: 1:10000
PurIF:ication:Affinity purIF:ication
Concentration:nan
Storage&Stability:-20°C/1 year
Background:This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to dIF:fer in their cellular localization and specIF:icity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
Subcellular Location.:Cell membrane; Single-pass type I membrane protein. Membrane raft ; Single-pass type I membrane protein. Endosome membrane ; Single-pass type I membrane protein. Subject to intracellular trafficking between the cell membrane and endosomes (PubMed:11231314). Localizes to cell surface lipid rafts (PubMed:18178838).
BiowMW:nan

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