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Myosin Heavy Chain, Smooth Muscle mouse mAb(ABT206)

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¥1900.00元/format:100ul

目录号:IML0822

库存:现货
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Catalog No. :IML0822
Reactivity:Human
Applications:IHC-p; IF(paraffin section)
Gene Name:MYH11 KIAA0866
Protein Name:Myosin Heavy Chain, Smooth Muscle
Human Gene Id:4629
Swiss-Prot:P35749
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.134% sodium azide.
Source:Monoclonal, Mouse:IgG1, Kappa
Dilution:IHC-p: 1:100-200 IF: 1:100-500
Purification:The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration:0.93mg:mL
Storage&Stability:-20°C:1 year
Background:The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alter
Subcellular Location:Colon, Smooth muscle, Breast
BiowMW:nan

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