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EnglishCatalog No. : | IML0103 |
Reactivity: | Human; Mouse |
Applications: | IHC-p; IF(paraffin section) |
Gene Name: | CALD1 CAD CDM |
Protein Name: | Caldesmon (CDM) |
Human Gene Id: | 800 |
Swiss-Prot: | Q05682 |
Formulation: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Source: | Monoclonal, Mouse:IgG2b, Kappa |
Dilution: | IHC-p: 1:100-1:200 IF: 1:50-1:200 |
Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Concentration: | 1mg:mL |
Storage&Stability: | -20°C:1 year |
Background: | This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. |
Subcellular Location: | Cytoplasmic |
BiowMW: | nan |
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