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AMACR (ABT-AMACR) mouse mAb

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¥1900.00元/format:100ul

目录号:IML0066

库存:现货
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Catalog No. :IML0066
Reactivity:Human; Mouse
Applications:IHC-p
Gene Name:AMACR
Protein Name:AMACR
Human Gene Id:23600
Swiss-Prot:Q9UHK6
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Monoclonal, Mouse:IgG1, Kappa
Dilution:IHC-p: 1:100-200
Purification:The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration:0.52mg:mL
Storage&Stability:-20°C:1 year
Background:This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.
Subcellular Location:Cytoplasmic
BiowMW:nan

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