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| Catalog No. ： | IML0043 |
| Reactivity： | Human |
| Applications： | IHC-p; IF(paraffin section) |
| Gene Name： | COL1A2 |
| Protein Name： | Collagen Type I |
| Human Gene Id： | 1278 |
| Swiss-Prot： | P08123 |
| Formulation： | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.61% sodium azide. |
| Source： | Monoclonal, Mouse:IgG2b, Kappa |
| Dilution： | IHC-p: 1:100-200 IF: 1:100-500 |
| Purification： | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Concentration： | 1mg:mL |
| Storage&Stability： | -20°C:1 year |
| Background： | This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. |
| Subcellular Location： | extracellular region,proteinaceous extracellular matrix,collagen trimer,collagen type I trimer,extracellular space,endoplasmic reticulum lumen,extracellular matrix,extracellular exosome, |
| BiowMW： | nan |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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