中文
EnglishCatalog No : | IPB14459 |
Reactivity: | Human; Mouse; |
Applications: | ELISA |
Dilution: | ELISA 1:10000-20000 |
Gene Name: | ngal |
Protein Name: | - |
Human Gene Id: | 3934 |
Swiss-Prot: | P80188 |
Formulation: | Liquid in PBS |
Source: | Nano-antibody with his-tag, Camel |
Purification: | The antibody was affinity-purified nickel column using his-tag in antibody |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Secreted Cytoplasmic granule lumen Cytoplasmic vesicle lumen Upon binding to the SLC22A17 (24p3R) receptor, it is internalized (By similarity) Releases the bound iron in the acidic lumen of cytoplasmic vesicles (PubMed:12453413, PubMed:20581821) |
MW: | - |
Background: | This gene encodes a protein that belongs to the lipocalin family Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores The presence of this protein in blood and urine is an early biomarker of acute kidney injury This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis Mice lacking this gene are more susceptible to bacterial infection than wild type mice |
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