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ApoB (Apolipoprotein B nano antibody

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¥1900.00元/format:100ul

目录号:IPB14458

库存:现货
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产品信息

Catalog No :IPB14458
Reactivity:Human; Mouse;
Applications:ELISA
Dilution:ELISA 1:10000-20000
Gene Name:APOB
Protein Name:Apolipoprotein B-100
Human Gene Id:338
Swiss-Prot:P04114
Formulation:Liquid in PBS
Source:Nano-antibody with his-tag, Camel
Purification:The antibody was affinity-purified nickel column using his-tag in antibody
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Cytoplasm Secreted Lipid droplet
MW:-
Background:This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA The two isoforms share a common N-terminal sequence The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels

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