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EnglishCatalog No : | IPB14456 |
Reactivity: | Human; Mouse; |
Applications: | ELISA |
Dilution: | ELISA 1:10000-20000 |
Gene Name: | TTR PALB |
Protein Name: | Prealbumin |
Human Gene Id: | 7276 |
Swiss-Prot: | P02766 |
Formulation: | Liquid in PBS |
Source: | Nano-antibody with his-tag, Camel |
Purification: | The antibody was affinity-purified nickel column using his-tag in antibody |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Secreted Cytoplasm |
MW: | 16170 |
Background: | transthyretin(TTR) Homo sapiens This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma The protein consists of a tetramer of identical subunits More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and:or the heart, and a small portion of the gene mutations is non-amyloidogenic The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc |
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