中文
EnglishCatalog No : | IPB14451 |
Reactivity: | Human; Mouse; |
Applications: | ELISA |
Dilution: | ELISA 1:10000-20000 |
Gene Name: | PDCD1 PD1 |
Protein Name: | Programmed cell death protein 1 (Protein PD-1) (hPD-1) (CD antigen CD279) |
Human Gene Id: | 5133 |
Swiss-Prot: | Q15116 |
Formulation: | Liquid in PBS |
Source: | Nano-antibody with his-tag, Camel |
Purification: | The antibody was affinity-purified nickel column using his-tag in antibody |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Cell membrane; Single-pass type I membrane protein |
MW: | - |
Background: | This gene encodes a cell surface membrane protein of the immunoglobulin superfamily This protein is expressed in pro-B-cells and is thought to play a role in their differentiation In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis Mice deficient for this gene bred on a BALB:c background developed dilated cardiomyopathy and died from congestive heart failure These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases |
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