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NMDARA2 rabbit pAb

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¥1900.00元/format:100ul

目录号:IPB14432

库存:现货
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Catalog No :IPB14432
Reactivity:Human; Mouse; Rat
Applications:WB
Dilution:WB: 1:500-2000
Gene Name:GRIN2A NMDAR2A
Protein Name:NMDARA2
Human Gene Id:2903
Swiss-Prot:Q12879
Formulation:Liquid in PBS containing 50% glycerol, and 071% sodium azide
Source:Rabbit
Purification:The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
Concentration:1 mg/ml
Storage&Stability:-20°C/1 year
Subcellular Location:Cell projection, dendritic spine Cell membrane; Multi-pass membrane protein Cell junction, synapse Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein Cytoplasmic vesicle membrane Expression at the dendrite cell membrane and at synapses is regulated by SORCS2 and the retromer complex
MW:161040
Background:This gene encodes a member of the glutamate-gated ion channel protein family The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation Alternative splicing results in multiple transcript variants

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