中文
EnglishCatalog No : | IPB14412 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB |
Dilution: | WB: 1:500-2000 |
Gene Name: | ADRBK1 BARK BARK1 GRK2 |
Protein Name: | GRK1/2 |
Human Gene Id: | 156 |
Swiss-Prot: | P25098 |
Formulation: | Liquid in PBS containing 50% glycerol, and 051% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Cytoplasm Cell membrane Cell junction, synapse, postsynapse Cell junction, synapse, presynapse |
MW: | 75790 |
Background: | The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart |
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