中文
EnglishCatalog No : | IPB14410 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB |
Dilution: | WB: 1:500-2000 |
Gene Name: | NACA HSD48 |
Protein Name: | NACA |
Human Gene Id: | 4666 |
Swiss-Prot: | Q13765 |
Formulation: | Liquid in PBS containing 50% glycerol, and 049% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Cytoplasm Nucleus The heterodimer is located mainly in the cytosol, and the homodimer in the nucleus |
MW: | 23650 |
Background: | This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC) This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum This protein is an IgE autoantigen in atopic dermatitis patients Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined There are multiple pseudogenes of this gene on different chromosomes |
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