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| Catalog No ： | IPB14393 |
| Reactivity： | Human; Mouse; Rat |
| Applications： | WB |
| Dilution： | WB: 1:500-2000 |
| Gene Name： | TLR3 |
| Protein Name： | TLR3 |
| Human Gene Id： | 7098 |
| Swiss-Prot： | O15455 |
| Formulation： | Liquid in PBS containing 50% glycerol, and 032% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | Endoplasmic reticulum membrane; Single-pass type I membrane protein Endosome membrane Early endosome |
| MW： | 99440 |
| Background： | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity TLRs are highly conserved from Drosophila to humans and share structural and functional similarities They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity The various TLRs exhibit different patterns of expression This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons It may thus play a role in host defense against viruses Use of alternative polyadenylation sites to generate |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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