中文
EnglishCatalog No : | IPB14392 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB |
Dilution: | WB: 1:500-2000 |
Gene Name: | DYRK2 |
Protein Name: | DYRK2/4 |
Human Gene Id: | 8445 |
Swiss-Prot: | Q92630 |
Formulation: | Liquid in PBS containing 50% glycerol, and 031% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Cytoplasm Nucleus Translocates into the nucleus following DNA damage |
MW: | 66110 |
Background: | DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and:or development The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro Two isoforms of DYRK2 have been isolated The predominant isoform, isoform 1, lacks a 5' terminal insert |
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