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| Catalog No ： | IPB14389 |
| Reactivity： | Human; Mouse; Rat |
| Applications： | WB |
| Dilution： | WB: 1:500-2000 |
| Gene Name： | STAT5A STAT5 |
| Protein Name： | STAT5A/B |
| Human Gene Id： | 6776 |
| Swiss-Prot： | P42229 |
| Formulation： | Liquid in PBS containing 50% glycerol, and 028% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | Cytoplasm Nucleus Translocated into the nucleus in response to phosphorylation |
| MW： | 87340 |
| Background： | The protein encoded by this gene is a member of the STAT family of transcription factors In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones Activation of this protein in myeloma and lymphoma associated with a TEL:JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis The mouse counterpart of this gene is found to induce the expression of BCL2L1:BCL-X(L), which suggests the antiapoptotic function of this gene in cells Alternatively spliced transcript variants have been |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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