中文
EnglishCatalog No : | IPB14387 |
Reactivity: | Human; Mouse; Rat |
Applications: | WB |
Dilution: | WB: 1:500-2000 |
Gene Name: | XRCC4 |
Protein Name: | XRCC4 |
Human Gene Id: | 7518 |
Swiss-Prot: | Q13426 |
Formulation: | Liquid in PBS containing 50% glycerol, and 025% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Nucleus Chromosome Localizes to site of double-strand breaks [Protein XRCC4, C-terminus]: Cytoplasm Translocates from the nucleus to the cytoplasm following cleavage by caspase-3 (CASP3) |
MW: | 36960 |
Background: | The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED) Alternative splicing generates several transcript variants [provided by RefSeq, Dec 2015], |
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