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| Catalog No ： | IPB14348 |
| Reactivity： | Human; Mouse; Rat |
| Applications： | WB |
| Dilution： | WB: 1:500-2000 |
| Gene Name： | ZP3 ZP3A ZP3B ZPC |
| Protein Name： | ZP3 |
| Human Gene Id： | 7784 |
| Swiss-Prot： | P21754 |
| Formulation： | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
| Source： | Rabbit |
| Purification： | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen |
| Concentration： | 1 mg/ml |
| Storage&Stability： | -20°C/1 year |
| Subcellular Location： | [Processed zona pellucida sperm-binding protein 3]: Zona pellucida Cell membrane; Single-pass type I membrane protein |
| MW： | 46640 |
| Background： | The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development The protein encoded by this gene is a structural component of the zona pellucida and functions in primary binding and induction of the sperm acrosome reaction The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a C-terminal consensus furin cleavage site, and a transmembrane domain It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix However, the requirement for furin cleavage in this process remains controversial based on mouse studies A variation in the last exon of this gene has previously served as the basis for an additional ZP3 locus; however, sequence and literature review reveals that there is only one full-length ZP3 locus in the human genome Another locus encoding a bipartite transcript designated POMZP3 contains a duplication of the last four exons of ZP3, including the above described variation, and maps closely to this gene |
SPECIES
APPLICATION
TITLE
Taizhou Baijia Biotechnology Co., Ltd. is a research and development company Production A biotechnology company whose main business is the sale of antibodies / recombinant proteins and related products. Have strict antibody production Quality inspection and quality control system, products cover the whole field of life science.
A103, Beide vaccine center, Binhe Road, west of Lujia Road
Taizhou pharmaceutical high tech Industrial Development Zone
Taizhou, Jiangsu, P.R.C
+8615216892345
bio100plus@126.com
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