中文
EnglishCatalog No : | IPB14179 |
Reactivity: | Human; Mouse; |
Applications: | WB |
Dilution: | WB: 1:500-2000 |
Gene Name: | ZFYVE1 DFCP1 KIAA1589 TAFF1 ZNFN2A1 PP10436 |
Protein Name: | ZFYV1 |
Human Gene Id: | 53349 |
Swiss-Prot: | Q9HBF4 |
Formulation: | Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide |
Source: | Rabbit |
Purification: | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen |
Concentration: | 1 mg/ml |
Storage&Stability: | -20°C/1 year |
Subcellular Location: | Golgi apparatus, Golgi stack Golgi apparatus Endoplasmic reticulum Lipid droplet Preautophagosomal structure Mitochondrion Resides predominantly in the cisternal stacks of the Golgi (PubMed:11256955) Colocalizes with TRIM13 on the perinuclear endoplasmic reticulum (PubMed:22178386) During starvation conditions, localizes to omegasomes which are endoplasmic reticulum connected strutures at the origin of preautophagosomal structures (PubMed:31293035, PubMed:25876663) Localizes to lipid droplets in the presence of oleic acid (PubMed:31293035, PubMed:30970241) |
MW: | 85470 |
Background: | The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate-containing membranes This protein contains two zinc-binding FYVE domains in tandem and is reported to localize to the Golgi apparatus Alternative splicing results in multiple transcript variants |
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